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Arthrogryposis multiplex (AM)

Arthrogryposis multiplex (AM) also known as ‘Curly Calf Syndrome’ was recognised in 2008.

The lethal condition causes calves to be born dead or die shortly after, exhibiting a curled or twisted spine and legs. AM calves typically have poor muscle development causing them to appear small and thin. The joints are commonly rigid, with the hind legs extended.

Controlled by a simple recessive mutation, AM causes a gene mutation leading to a missing segment of DNA. This missing segment affects two genes, one of which is involved in the nerve and muscle development which causes the calves to express the characteristic features of ‘Curly Calf Syndrome’.


Further readingĀ 

American Angus Association Iowa State University